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CAD Antibody

Rabbit Polyclonal Antibody

Cat. No.

250567

Unit

0.1 mg

Price $307.00

Order

Order directly from

Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Caspase-activated deoxyribonuclease (CAD) also is designated as DNA fragmentation factor 40 kDa subunit (DFF40) and caspase-activated DNase. CAD is a nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. CAD degrades naked DNA and induces apoptotic morphology. CAD subunits of 45 and 40 kDa form heterodimers.

Spec Container

Datasheet

Data Left

Isotype

Rabbit Ig

Applications

IHC

Species Reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Alternate Names

DNA fragmentation factor subunit beta; DNA fragmentation factor 40 kDa subunit; DFF-40; Caspase-activated deoxyribonuclease; Caspase-activated Dnase; CAD; Caspase-activated nuclease; CPAN; DFFB; DFF2; DFF40

Data Right

Accession No.

O76075

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of mouse CAD.

Application Notes

E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Images

CAD staining in rat brain. Formalin-fixed paraffin-embedded rat brain tissue is stained with CAD Antibody (Cat. No. 250567) used at 1:200 dilution.

Citations

Product Citations

Zhdanov D et al. 2015. DNA Cell Biol. 34(5): 316-26. PMID 25849439.

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For research use only, not for diagnostic or therapeutic procedures.

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