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CULLIN Antibody

Rabbit Polyclonal Antibody
Cat. No. 
250489
Unit 
0.1 mg
Price $323.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Cullin (Cullin-1, CUL1) is a core component of multiple cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, cullin serves as a rigid scaffold that organizes the SKP1-F-box protein and RBX1 subunits. Cullin contributes to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.