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Fibronectin receptor Antibody

Rabbit Polyclonal Antibody
Cat. No. 
251680
Unit 
0.1 mg
Price $330.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

***DISCONTINUED, REPLACED WITH CAT. NO. 250731 AND 251162***

ITGA5 (Integrin alpha-5) is a 115-kDa transmembrane glycoprotein. Integrin alpha-5 subunit is the common alpha-5 chain of the very late antigen (VLA) forming a non-covalent heterodimeric complex with the integrin beta-1 subunit, a receptor for fibrinogen and extracellular matrix proteins such as fibronectin. Alpha-5/beta-1 integrin is an important adhesion molecule involved in cell-cell and cell-extracellular matrix interactions by recognizing the RGD canonical sequence in ligands. In addition to adhesion, integrins are known to participate in cell-surface mediated signaling.