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Integrin Alpha-V Beta-3 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
251672
Unit 
0.1 mg
Price $323.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Integrin alpha-V/beta-3, also called vitronectin receptor or CD51/CD61, belongs to the integrin protein family that participates in cell adhesion and cell-surface mediated signalling by forming heterodimers of alpha and beta integrin chains. Integrin alpha-V/beta-3 is a receptor for cytoactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins recognize the sequence RGD in a wide array of ligands. Defects in CD61 are a cause of Glanzmann thrombasthenia, a blot clot disorder.