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Munc-18 (Ser515) Antibody

Phosphospecific Antibody
Rabbit Polyclonal Antibody
Cat. No. 
0.1 ml
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Otwo Biotech (Shenzhen) Inc.

Ste 518, 5th Bldg, Chuangye Rd
Zhongxing Industrial Park, Nanshan District
Shenzhen 518054

Phone: 0755-26055215
Fax: 0755-86372180

Syntaxin-binding protein 2 (Munc-18) is involved in intracellular vesicle trafficking and vesicle fusion with membranes. Munc-18 contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Munc-18 regulates cytotoxic granule exocytosis in natural killer (NK) cells. The function of Munc-18 is regulated by PKC phosphorylation of Ser515.