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p38 MAPK (Thr180/Tyr182) Antibody

Phosphospecific Antibody
Rabbit Polyclonal Antibody
Cat. No. 
0.1 ml
Price $405.00


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San Diego, CA 92126, USA

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Mitogen-activated protein kinase p38 alpha (p38 MAPK) responds to activation by environmental stress, pro-inflammatory cytokines and lipopolysaccharide (LPS) by phosphorylating a number of transcription factors, such as ELK1 and ATF2 and several downstream kinases, such as MAPKAPK2 and MAPKAPK5. P38 MAPK plays a critical role in the production of some cytokines, for example IL-6. P38 MAPK plays a role in stabilization of EPO mRNA during hypoxic stress. p38 MAPK is activated by a dual specificity kinase that phosphorylates Thr180 and Tyr182.