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Pancreatic Polypeptide Antibody

Mouse Monoclonal Antibody
Cat. No. 
250242
Unit 
0.2 mg
Price $911.00

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Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
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Description 

Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors. This antibody binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.