Pancreatic Polypeptide Antibody
Mouse Monoclonal Antibody
Cat. No.
250242
Unit
0.2 mg
Price
$911.00
Order
Order directly from
Abbiotec
350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA
Phone: 1 858 586 0500 x100,
1 800 854 7453
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors. This antibody binds human full length pancreatic polypeptide. Cross-reactivity with NPY and PYY was <0.1%.