Ph. 858 586 0500    Toll Free 800 854 7453

PHM Antibody

Mouse Monoclonal Antibody
Cat. No. 
0.2 mg
Price $911.00


Order directly from


7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Human peptide histidine-methionine (PHM) is a 27-amino-acid peptide belonging to the glucagon-secretin family of peptide hormones. PHM is produced from the same prohormone as VIP, with which it shows considerable sequence homology. The VIP/PHM prohormone is produced by neurons in the central and peripheral nervous systems, often together with acetylcholine. In some situations the effect of the peptides is to reinforce and prolong the effects of neurotransmitter release. Like VIP, PHM is a vasodilator and stimulator of intestinal fluid secretion. High plasma levels of PHM are diagnostic of the corresponding peptide-producing tumor (VIPoma), associated with the watery diarrhea-hypokalemia-achlorhydria syndrome. This antibody binds human PHM and cross-reacts with PACAP (approximately 12%, incomplete non-parallel inhibition). This antibody does not cross-react with GLP-1, GLP-2, VIP or glucagon.