Ph. 858 586 0500    Toll Free 800 854 7453

Testicular Receptor 2 Antibody

Rabbit Polyclonal Antibody
Cat. No. 
0.1 ml
Price $308.00


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350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Testicular receptor 2 (TR2) is a member of the orphan nuclear receptor family. TR2 is widely expressed at a low level throughout the adult testis. TR2 represses transcription and binds DNA, directly interacting with HDAC3 and HDAC4 via DNA-binding domains. TR2 has also been implicated in regulation of estrogen receptor activity in mammary glands. TR2 forms a heterodimer with TR4 that can bind to the direct repeat 6 element of the hepatitis B virus (HBV) enhancer II region thus suppressing HBV gene expression.