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Thrombin (5G9) Antibody

Mouse Monoclonal Antibody
Cat. No. 
250341
Unit 
0.2 mg
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Otwo Biotech (Shenzhen) Inc.

Ste 518, 5th Bldg, Chuangye Rd
Zhongxing Industrial Park, Nanshan District
Shenzhen 518054

Phone: 0755-26055215
Fax: 0755-86372180
Email: sales@otwobiotech.com
Description 

Thrombin is the active enzyme that splits fibrinogen into fibrin in final stage of blood coagulation. It is generated from its circulating inactive precursor, prothrombin, by the action of factor Xa aided by factor Va, phospholipid and calcium ions. Thrombin is a glycoprotein formed by a 6-kDa A chain linked by a disulfide bridge to a 31-kDa B chain which carries the serine protease catalytic site. This antibody binds to human thrombin and to complexes of human thrombin with the thrombin inhibitor hirudin. No cross-reaction is seen with prothrombin. Cross-reactivity with thrombin from other species has not been tested.