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Tyrosine 3-hydroxylase Antibody

Mouse Monoclonal Antibody
Cat. No. 
251807
Unit 
0.1 mg
Price $307.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 

Tyrosine 3-hydroxylase (TH) plays a role in the physiology of adrenergic neurons, catalyzing the following reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4a-hydroxytetrahydrobiopterin. Defects in TH are the cause of dystonia DOPA-responsive autosomal recessive (ARDRD) also known as autosomal recessive Segawa syndrome. ARDRD is a form of DOPA-responsive dystonia presenting in infancy or early childhood. Dystonia is defined by the presence of sustained involuntary muscle contractions, often leading to abnormal postures.