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WDR5 (7B11) Antibody

Mouse Monoclonal Antibody
Cat. No. 
253033
Unit 
0.1 ml
Price $339.00

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350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
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Email: info@abbiotec.com
Description 
WDR5 (WD repeat-containing protein 5) belongs to the family of WD-40 repeat protein. It is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.