Human NGF- Beta

Recombinant Active Protein

Cat. No.

600161

Unit

0.02 mg

Price $250.00

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Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453

Fax: 1 858 586 6252

Email: info@abbiotec.com

Website: http://www.abbiotec.com

Description

Human NGF-beta is a neurotrophic factor related to BDNF, NT-3 and NT-4. Human NGF-beta acts as a neurotrophic factor through its receptor beta-NGFR. This cytokine stimulates division and differentiation of sympathetic and embryonic sensory neurons, and is also involved in the growth and differentiation of B lymphocytes and B-cell survival. Human NGF-beta is a noncovalently disulfide-linked homodimer consisting of 121 amino acids with a MW of 2 x 13.6 kDa.

Spec Container

Datasheet

Format

Each vial contains 20 ug of lyophilized protein. Reconstitute with 0.2 ml sterile deionized water for a final concentration of 0.1 mg/ml.

Alternate Names

Beta-Nerve growth factor; Beta NGF; NGF; NGFB

Accession No.

P01138

13600 Da

Sequence

MSSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRR

Source

E. coli. Endotoxin level as measured by LAL is <0.01ng/ug or <0.1EU/ug.

Purity

Purity > 97% as determined by RP-HPLC and reducing and non-reducing SDS-PAGE. Protein Content determined by RP-HPLC calibrated against a known standard and quantitation on SDS-PAGE against a known standard.

Application Notes

Biological activity is determined by the ability to stimulate neurite growth in chick E9 DRG cells. The ED50 is < 1.0 ng/ml.

Storage

Store at -20°C. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. We recommend to add a carrier protein (0.1% HSA or BSA) for long term storage.

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For research use only, not for diagnostic or therapeutic procedures.

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Human NGF- Beta

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