Ph. 858 586 0500    Toll Free 800 854 7453

Human Rank Ligand

Recombinant Active Protein
Cat. No. 
600166
Unit 
0.01 mg
Price $250.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
RANK ligand (RANKL) is a cytokine that binds to TNFRS11B/OPG and to TNFGS11A/RANK This cytokine also augments the ability of dendritic cells to stimulate naïve T-cell proliferation, is an important regulator of interactions between T-cells and dendritic cells, and plays a role in the regulation of the T-cell-dependent immune response. RANKL is an osteoclast differentiation and activation factor and enhances bone resosrption in humoral hypercalcemia of malignancy. Recombinant human soluble RANKL produced in E. coli is a single non-glycosylated polypeptide chain containing 176 amino acids with a MW of 20,006 Da.