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Human SDF-1-beta

Recombinant Active Protein
Cat. No. 
600230
Unit 
0.01 mg
Price $250.00

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Abbiotec

7985 Dunbrook Rd., Ste A
San Diego, CA 92126, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Stromal Derived Growth Factor-1-beta (SDF-1-beta) is an important chemoattractant for T-lymphocytes and monocytes, but does not activate neutrophils. It activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. SDF-1-beta decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. The human amino acid sequence shares 100% homology to the feline SDF-1-beta. Recombinant H-SDF-1-beta is a polypeptide chain comprised of 72 amino acids with a MW of 8,526 Da.