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Mouse NT-3

Recombinant Active Protein
Cat. No. 
600351
Unit 
0.01 mg
Price $250.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
Neurotrophin-3 (NT-3) is an important member of the nerve growth factor (NGF) family of proteins behind BDNF and NGF. It is thought to promote the survival or differentiation of existing and new neurons in the central nervous system and synapses. These functions are thought to be communicated by TrkC, a receptor tryrosine kinase thought to induce NT-3-specific signaling. In addition, NT-3 is thought to also bind TrkB and low affinity nerve growth factor receptor (LNGFR). Mouse NT-3 is produced in E.coli. Recombinant mouse NT-3 is a non-glycosylated, non-covalently linked homodimer, containing two 119 amino acid chains, with a total molecular weight of 27.2 kDa.