Ph. 858 586 0500    Toll Free 800 854 7453

Mouse Rank Ligand

Recombinant Active Protein
Cat. No. 
600210
Unit 
0.01 mg
Price $250.00

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Abbiotec

350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Description 
RANK Ligand (RANKL) occurs in 3 forms: cell-bound RANKL, which is expressed by osteoblast lineage cells, soluble RANKL, which is expressed by activated T lymphocytes, and a truncated ectodomain form derived from the cell-bound RANKL, which is enzymatically processed by TACE. All three forms stimulate their specific receptors, TNFRSF11B/OPG and TNFRSF11A/RANK, which are located on osteoclastic and dendritic cells. RANKL is critically involved in osteoclastic function, and in the regulation of specific immunity. Recombinant M-sRANK Ligand is approximately 19.9 kDa and contains 174 amino acids.