Recombinant Active Protein
Monocyte Chemotactic Protein 1 (MCP-1), also known as CCL2, is thought to be produced by injured or infected tissues. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. Rat MCP-1 is produced in E.coli. Recombinant rat MCP-1 is a non-glycosylated protein, containing 125 amino acids, with a molecular weight of 14.1 kDa.