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NOGO Antibody

Rabbit Polyclonal Antibody
Cat. No. 
251677
Unit 
0.1 mg
Price $292.00

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Order directly from

Abbiotec

938 S. Andreasen Dr., Ste I
Escondido, CA 92029, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Email: info@abbiotec.com
Website: http://www.abbiotec.com
Description 
Neurite outgrowth inhibitor (NOGO) plays a role both in the restriction of axonal regeneration after injury and in structural plasticity in the CNS. Isoform 2 of NOGO reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 of NOGO inhibit BACE1 activity and amyloid precursor protein processing.

Spec Container

For research use only, not for diagnostic or therapeutic procedures.