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Human TNF-R1

Recombinant Protein
Cat. No. 
0.01 mg
Price $250.00


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350 W. 9th Ave., Ste 107
Escondido, CA 92025, USA

Phone: 1 858 586 0500 x100,
1 800 854 7453
Fax: 1 858 586 6252
Two types of soluble TNF receptors (sTNF-R1 and sTNF-R2) have been identified which act to neutralize the biological activities of TNF alpha and TNF beta. Levels of these soluble receptors appear to arise as a result of shedding of the extracellular domains of the membrane bound receptors. Elevated levels of soluble TNF receptors have been found in the amniotic fluid of pregnant women. Recombinant sTNF-R1 comprises a 161 amino acid fragment (41-201) corresponding to the mature TNF-R1 protein and is expressed in E. coli with an amino-terminal hexahistidine tag.